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Sustanon 250: Sustanon 250 is a combination of four testosterone esters that is hardly ever prescribed medically in the United States. It has been extensively studied in a large animal cohort and in vitro. Sustanon 250 is an analogue of testosterone with comparable and even higher half-lives and greater bioavailability. The oral bioavailability of Sustanon 250 is about 70% and the bioavailability of its analogues is about 30% with a mean half-life of 1.6–2.0 hours. The concentration of the bioactive steroid has been decreased from 10–100 ng/ml to <1 ng/ml in the placebo and its mean half-life has increased from >8 hours to >17 hours. The peak plasma concentration occurs approximately 7 hours after dosing. Testosterone is converted in the liver to its active metabolite, dihydrotestosterone, and this effect is blocked, but the conversion process is not complete. The plasma concentration of dihydrotestosterone is increased (approximately 0.2–0.5 mg/dl) for 7 hours following an intravenous injection of 100 ng Testosterone Enanthate in adult men. In a placebo-controlled study in men older than 65 years of age who were receiving testosterone enanthate and had been taking concomitant oral contraceptives or oral contraceptives plus progestin for 7 or 14 days, Testosterone Enanthate (1.25 mg/kg/day) was administered by a standard parenteral route. Twenty-six subjects received the Testosterone Enanthate (0.75 or 1.6 mg/kg/day) and 26 received placebo. All subjects received Testosterone Enanthate for 7 days and then at 10 days post-dosing. The mean total daily dose of testosterone was 2.2 mg/day after 1 day, 3.2 mg/day after 2 days and 4.4 mg/day after 3 days of treatment. The peak plasma concentration, after 1 day of treatment, was 13.4 ng/dl (range 4–13.8 ng/dl) with a mean half-life of 6–8 hours. The increase in plasma and intracellular concentrations is significantly inhibited by a combination of both the antiestrogen, levonorgestrel, and nonsteroidal anti-inflammatory agents. In the study design of Sustanon, the duration and the daily dose of Testosterone Enanthate will be adjusted in the clinical trial. In a larger human study, Sustanon was used for the first time in an adult male on the verge of his 50th birthday. At 1 year and 7 months Similar articles:
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